Yes, astronauts frequently collaborate with astronomers and astrophysicists. Such collaborations are vital for the success of space missions and scientific research. Astronomers and astrophysicists are often responsible for developing the theoretical framework and scientific goals for missions, identifying celestial phenomena or targets for observation. They analyze data and provide insights that guide mission objectives and experiments.

Astronauts, on the other hand, often apply their skills during the execution of missions, particularly those that involve complex operational tasks aboard the International Space Station (ISS) or during specialized space missions. They carry out experiments, operate telescopes, and install or repair equipment designed by astronomers and astrophysicists. This teamwork is essential for the seamless flow from planning to execution in space science endeavors, allowing for significant advancements in our understanding of the universe.

An example of this collaboration can be seen in the operations of the Hubble Space Telescope, where astronauts have played crucial roles in servicing and upgrading equipment designed by astronomers and astrophysicists. Additionally, many astronauts have backgrounds in astrophysics and related fields, further bridging the roles between these professionals. This integrated approach enhances the scope and impact of space research and exploration.